An Antisense Amido-Bridged Nucleic Acid Gapmer Oligonucleotide Targeting SRRM4 Alters REST Splicing and Exhibits Anti-tumor Effects in Small Cell Lung Cancer and Prostate Cancer Cells

Ser/Arg repetitive matrix 4 (SRRM4) expression and RE1-silencing transcription factor (REST) splicing were analyzed by RT-qPCR and conventional RT-PCR after treating SRRM4 antisense oligonucleotide, and cell viability was analyzed in vitro.
[Cancer Cell International]
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