Allogeneic BCMA-Targeting CAR T Cells in Relapsed/Refractory Multiple Myeloma: Phase I UNIVERSAL Trial Interim Results
Investigators evaluated escalating doses of ALLO-715 after lymphodepletion with an anti-CD52 antibody (ALLO-647)-containing regimen in 43 patients with relapsed/refractory multiple myeloma.
[Journal Of Cell Biology] Using an innovative planar-sagittal live imaging technique to visualize the basement membrane of developing skin, researchers directly observed basement membrane deformation during hair follicle budding and basal progenitor cell divisions.
[Nature Genetics] Scientists studied the impact of the apolipoprotein B mRNA-editing catalytic subunit-like (APOBEC) enzyme APOBEC3B on epidermal growth factor receptor-driven lung cancer.
[European Journal Of Pharmacology] The angiotensin (Ang)-(1–7)-/Mas axis inhibited TGF-β1-induced lung fibroblast differentiation, inflammation, and fibrosis in bleomycin-treated lung tissue.