NewslettersHuman Immunology NewsCD28-CAR-T Cell Activation through FYN Kinase Signaling Rather Than LCK Enhances Therapeutic PerformanceBy Laurisa Dohm - January 24, 20230560Scientists found that LCK-deficient CAR-T cells were strongly signaled through CAR and had better in vivo efficacy with reduced exhaustion phenotype, as well as enhanced induction of memory and proliferation.[Cell Reports Medicine]Full ArticleGraphical Abstract