NewslettersHuman Immunology NewsBTG1 Mutation Yields Supercompetitive B Cells Primed for Malignant TransformationBy Laurisa Dohm - January 24, 20230504By studying primary human lymphomas and developing new mouse models, scientists found that mutations affecting BTG1 disrupted a critical immune gatekeeper mechanism that strictly limited B cell fitness during antibody affinity maturation.[Science]Full Article