Loss of β-Catenin Causes Cementum Hypoplasia by Hampering Cementogenic Differentiation of Axin2-Expressing Cells

The authors evaluated the effects of β-catenin deletion in Axin2+ cells on cementogenesis. They generated triple transgenic mice to conditionally delete β-catenin in Axin2-lineage cells by crossing Axin2CreERT2/+; R26RtdTomato/+ mice with β-cateninflox/flox mice.