Glycolytic Pfkp Acts as a Lin41 Protein Kinase to Promote Endodermal Differentiation of Embryonic Stem Cells

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Scientists established an intersection between LIF-Stat3 signaling that was essential for maintaining mESC pluripotency, and the glycolytic enzyme, the platelet isoform of phosphofructokinase (Pfkp).
[EMBO Reports]
AbstractGraphical Abstract