VGLL4-TEAD1 Promotes Vascular Smooth Muscle Cell Differentiation from Human Pluripotent Stem Cells via TET2

Using microarray profiling, investigators found that the Hippo pathway components vestigial-like family member 4 (VGLL4) and TEA domain transcription factor 1 (TEAD1) were upregulated during vascular smooth muscle cell differentiation from H1 ESCs.