Interleukin-18-Primed Human Umbilical Cord-Mesenchymal Stem Cells Achieve Superior Therapeutic Efficacy for Severe Viral Pneumonia via Enhancing T-Cell Immunosuppression

Researchers selected an appropriate cytokine, IL-18, based on the special cytokine expression profile in severe pneumonia of mice induced by H1N1virus to prime human umbilical cord-MSCs in vitro and improved the therapeutic effect of hUC-MSCs in vivo.