[Experimental & Molecular Medicine] The authors showed that MSC-derived small extracellular vesicles specifically convert T helper 17 cells into IL-17 low-producer cells by degrading RAR-related orphan receptor γt at the protein level.
[Fierce Biotech] In draft guidance, the FDA outlined plans to move away from single-arm studies and instead favor randomized controlled trials that can potentially serve as the basis for both accelerated and full approval.