Lysyl Hydroxylase LH1 Promotes Confined Migration and Metastasis of Cancer Cells by Stabilizing Septin2 to Enhance Actin Network

LC–MS was applied to determine the differentially expressed proteins between hepatocellular carcinoma tissues and corresponding adjacent tissue. Collective migration and single cell migration microfluidic devices with 6 μm-high confined channels were designed and fabricated to mimic the in vivo confined space.