LMP1 Mediates Tumorigenesis through Persistent Epigenetic Modifications and PGC1β Upregulation

Researchers investigated the potential mechanism for transient EBV/LMP1 exposure‑mediated persistent peroxisome proliferator‑activated receptor‑γ coactivator‑1β (PGC1β) expression and subsequent tumorigenesis through modification of mitochondrial function.