PVT1/miR-136/Sox2/UPF1 Axis Regulates the Malignant Phenotypes of Endometrial Cancer Stem Cells

Investigators found that plasmacytoma variant translocation 1 (PVT1) was highly expressed in endometrial cancers and endometrial CSCs (ECSCs), correlated with poor patient prognosis, promoted the malignant behavior and the stemness of endometrial cancer cells and ECSCs.