Development of Engineered CAR T Cells Targeting Tumor-Associated Glycoforms of MUC1 for the Treatment of Intrahepatic Cholangiocarcinoma

Scientists suggested the CAR T cells could specifically eliminate Tn-MUC1-positive ICC cells, but not Tn-MUC1-negative intrahepatic cholangiocarcinoma cells, in vitro and in vivo.
[Journal Of Immunotherapy]
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