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e.g. organoids

Inhibiting SCD Expression by IGF1R during Lorlatinib Therapy Sensitizes Melanoma to Ferroptosis

The authors used a drug synergy screen that combined a ferroptosis inducer, RSL3, with 240 anti-tumor drugs from the FDA-approved drug library and identified lorlatinib to synergize with RSL3 in melanoma cells.
[Redox Biology]
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