STOML2 Restricts Mitophagy and Increases Chemosensitivity in Pancreatic Cancer through Stabilizing PARL-Induced PINK1 Degradation
Using a tissue microarray, scientists found that high stomatin-like protein 2 (STOML2) expression was correlated with higher survival of patients with pancreatic cancer.
[Journal Of Experimental Medicine] Single-cell RNA sequencing confirmed a common developmental trajectory between the thymic and blood unconventional T cells and clearly delineated this unconventional lineage in blood.
[Journal Of Experimental Medicine] Scientists showed that in pancreatic ductal adenocarcinomas (PDAC), proliferation of tumor-associated macrophagess could be driven by colony stimulating factor-1 produced by cancer-associated fibroblasts.
[Cancer Cell] Researchers examined the microenvironment in glioma and foundd that tumor-infiltrating T cells were mainly confined to the perivascular cuffs and expressed high levels of CCR5, CXCR3, and programmed cell death protein 1.