Copper Overload Impairs HSPC Proliferation via Inducing HSF1/SP1 Aggregation and the Subsequently Downregulating FOXM1-Cytoskeleton Axis

Investigators reported a novel association and the novel potential pathways for copper overload to induce proliferation defects in zebrafish embryonic hematopoietic stem and progenitor cells (HSPCs) via down-regulating expression of foxm1-cytoskeleton axis.

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