Combinatorial Treatment Rescues Tumor-Microenvironment-Mediated Attenuation of MALT1 Inhibitors in B-Cell Lymphomas

The authors used >1,100 diffuse large B-cell lymphoma patient samples to determine immune and extracellular matrix cues in the lymphoid tumour microenvironment, and built representative synthetic-hydrogel-based B-cell-lymphoma organoids accordingly.
[Nature Materials]

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