An XBP1s–PIM-2 Positive Feedback Loop Controls IL-15–Mediated Survival of Natural Killer Cells

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By using spliced X-box–binding protein 1 (XBP1s) conditional knockout mice, scientists found that XBP1s was critical for IL-15–mediated natural killer cell survival, but not proliferation, in vitro and in vivo.
[Science Immunology]
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