A Monoclonal Trd Chain Supports the Development of the Complete Set of Functional γδ T Cell Lineages

To better understand the role of the γδ T cell receptor (TCR), investigators generated an orthotopic TCRδ transgenic mouse model. They demonstrated a multi-layered functionality of γδ TCRs and diverse roles of CDR3δ-mediated selection during γδ T cell development.
[Cell Reports]
Full ArticleGraphical Abstract

Stay up-to-date with your field!

Subscribe for free weekly science newsletters.

Related News