Inflammatory Stimuli Induce Shedding of Heparan Sulfate from Arterial but Not Venous Porcine Endothelial Cells Leading to Differential Proinflammatory and Procoagulant Responses

Using a 3D round-channel microfluidic system, the authors investigated the endothelial glycocalyx, particularly heparan sulfate, on porcine arterial and venous endothelial cells.