NewslettersPancreatic Cell NewsSpontaneously Evolved Progenitor Niches Escape Yap Oncogene Addiction in Advanced Pancreatic Ductal AdenocarcinomasBy Bob - March 21, 2023083By employing an inducible genetic engineered mouse model, the authors illustrated that lineage plasticity enabled advanced PDAC tumors to develop spontaneous relapse following elimination of the central oncogenic driver, Yap.[Nature Communications]Full Article