Combined Disruption of T Cell Inflammatory Regulators Regnase-1 and Roquin-1 Enhances Antitumor Activity of Engineered Human T Cells

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Researchers targeted a regulatory axis of T cell inflammatory responses, Regnase-1 and Roquin-1, to enhance antitumor responses in human T cells engineered with two clinical-stage immune receptors.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
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