A Metabolism Targeting Three-Pronged Attack Significantly Attenuates Breast Cancer Stem Cell Related Markers toward Therapeutic Application

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To understand the role of metabolic pathways in in cancer cell survival and proliferation, investigators targeted glycolysis, pentose phosphate pathway, and mitochondria using three different inhibitors: 2-deoxyglucose, 6-aminonicotinamide, and doxycycline, separately and in combination.
[Biomedicine & Pharmacotherapy]
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