DAB2IP-Knocking Down Resulted in Radio-Resistance of Breast Cancer Cells Is Associated with Increased Hypoxia and Vasculogenic Mimicry Formation

Small RNA interference system was employed to decrease DOC-2/DAB2 interactive protein (DAB2IP) expression in two breast cancer cell lines, MDA-MB-231 and 4T1. Cells in response to IR or antineoplastics were detected by clone formation assay or MTT method, respectively.