Discovery of YH677 as a Cancer Stemness Inhibitor That Suppresses Triple-Negative Breast Cancer Growth and Metastasis by Regulating the TGFβ Signaling Pathway

Harmine was identified as a hit compound based on phenotypic screening of a 2D assay and patient-derived organoid model that was established from a patient with multiple drug resistance and breast metastases.
[Cancer Letters]

Stay up-to-date with your field!

Subscribe for free weekly science newsletters.

Related News