Mesenchymal Stem Cell-Derived Extracellular Vesicles Subvert Th17 Cells by Destabilizing RORγt through Posttranslational Modification

The authors showed that MSC-derived small extracellular vesicles specifically convert T helper 17 cells into IL-17 low-producer cells by degrading RAR-related orphan receptor γt at the protein level.
[Experimental & Molecular Medicine]
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