Thioredoxin Facilitates Hepatocellular Carcinoma Stemness and Metastasis by Increasing BACH1 Stability to Activate the AKT/mTOR Pathway

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Functional studies showed that thioredoxin promoted hepatocellular carcinoma (HCC) stemness properties and facilitated HCC metastasis both in vitro and in vivo.
[FASEB Journal]
Abstract