Breast Cancer Stem Cell–Derived Tumors Escape from γδ T-Cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands

Investigators showed that patient-derived triple-negative breast CSCs were efficiently recognized and killed by ex vivo expanded γδ T cells from healthy donors. Orthotopically xenografted BCSCs, however, were refractory to γδ T-cell immunotherapy.