Immune Checkpoint B7-H3 Is a Therapeutic Vulnerability in Prostate Cancer Harboring PTEN and TP53 Deficiencies

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Researchers sought in vivo genetic evidence for, and mechanistic understanding of, the role of B7 homolog 3 protein (B7-H3) in PTEN/TP53-deficient prostate cancer.
[Science Translational Medicine]
AbstractPress Release