Mechanical Pressure-Induced Dedifferentiation of Myofibroblasts Inhibits Scarring via SMYD3/ITGBL1 Signaling

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Scientists demonstrated that human scar-derived myofibroblasts dedifferentiatde into normal fibroblasts in response to pressure therapy, and identified how SMYD3/ITGBL1 contributed to the nuclear relay of mechanical signals.
[Developmental Cell]
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