The PLOD2/Succinate Axis Regulates the Epithelial–Mesenchymal Plasticity and Cancer Cell Stemness

By
Noshin Noorjahan
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Using stable isotope-resolved metabolomics analysis, the authors showed that the epithelial mesenchymal transition was associated with profound changes in metabolites, including elevation of cytoplasmic succinate levels.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
Abstract