MutSα and MutSβ as Size-Dependent Cellular Determinants for Prime Editing in Human Embryonic Stem Cells

Through homozygous knockout of MMR pathway key proteins MSH2, MSH3, and MSH6, scientists revealed that MutSα and MutSβ determined prime editor efficiency in an editing size-dependent manner.
[Molecular Therapy – Nucleic Acids]
AbstractGraphical Abstract

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