A High-Throughput 3D Cantilever Array To Model Airway Smooth Muscle Hypercontractility in Asthma Scilightfeatured

Using DEFLCT, researchers exposed primary human airway smooth muscle cell-derived microtissues to a panel of six inflammatory cytokines present in the asthmatic niche, identifying TGF-β1 and IL-13 as inducers of a hypercontractile phenotype.