Engineering Homologous Platelet-Rich Plasma, Platelet-Rich Plasma-Derived Exosomes, and Mesenchymal Stem Cell-Derived Exosomes-Based Dual-Crosslinked Hydrogels as Bioactive Diabetic Wound Dressings

The authors developed novel dual-crosslinked hydrogels based on the silk proteins (SPs) sericin and fibroin, including SP@PRP, SP@MSC-Exos, and SP@PRP-Exos, to promote diabetic wound healing synergistically.