Human Umbilical Cord-Derived Mesenchymal Stem Cells Alleviate Oxidative Stress-Induced Islet Impairment via the Nrf2/HO-1 Axis
Investigators showed that intravenous injection of human umbilical cord-MSCs engrafted into the injured pancreas and promoted pancreatic β-cell function in a mouse model of type 1 diabetes mellitus.
[Cell & Bioscience] Scientists demonstrated that CDK1 was correlated with prognosis and was highly expressed in pancreatic cancer tissue and gemcitabine-resistant cells
[Acta Biomaterialia] Researchers demonstrated that incorporating human pancreatic decellularized extracellular matrix within alginate microcapsules resulted in a significant increase in Glucose Stimulation Index and total insulin secreted by encapsulated human islets, compared to free islets and islets encapsulated in only alginate.
[Cancer Letters] In vivo and in vitro experiments revealed that FABP4 induced macrophage-related inflammation to promote pancreatic cancer cell migration, invasion, and metastasis under obese condition.