An rRNA Fragment in Extracellular Vesicles Secreted by Human Airway Epithelial Cells Increases the Fluoroquinolone Sensitivity of P. aeruginosa

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Researchers showed that extracellular vesicles secreted by primary human alveolar epithelial cells transfered multiple distinct sRNA fragments to P. aeruginosa that were predicted to target the three subunits of the fluoroquinolone efflux pump MexHI-OpmD, thus increasing antibiotic sensitivity.
[American Journal Of Physiology-Lung Cellular And Molecular Physiology]
Abstract