Targeting Long Non-Coding RNA MALAT1 Reverses Cancerous Phenotypes of Breast Cancer Cells through microRNA-561-3p/TOP2A Axis

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Researchers determined the correlation between miR-561-3p and metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and their roles in breast cancer (BC) progression. The expression of MALAT1, mir-561-3p, and topoisomerase alpha 2 (TOP2A) as a target of miR-561-3p was determined in BC clinical samples and cell lines via qRT-PCR.
[Scientific Reports]
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