Monocyte-Derived IL-6 Programs Microglia to Rebuild Damaged Brain Vasculature

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Cerebrovascular repair did not occur in interluekin (IL)-6 knockouts or in mice lacking microglial IL-6Ra expression, and single-cell transcriptomic analyses revealed faulty repair-associated microglia programming in the absence of IL-6 signaling.
[Nature Immunology]
Abstract