Anti-Warburg Effect via Generation of ROS and Inhibition of PKM2/β-Catenin Mediates Apoptosis of Lambertianic Acid in Prostate Cancer Cells

To elucidate the underlying antitumor mechanism of lambertianic acid (LA) derived from Pinus koraiensis, the role of cancer metabolism related molecules was investigated in the apoptotic effect of LA in DU145 and PC3 prostate cancer cells.