Single-Cell RNA-Seq Uncovers Distinct Pathways and Genes in Endothelial Cells during Atherosclerosis Progression

ScRNA-seq data of cells from atherosclerotic human coronary arteries were analyzed using the Seurat package. Cell types were clustered, and differentially expressed genes were screened. Gene Set Variation Analysis scores of hub pathways were compared among different cell clusters.

[Frontiers in Molecular Biosciences]