The HPV8 E6 Protein Targets the Hippo and Wnt Signaling Pathways as Part of Its Arsenal To Restrain Keratinocyte Differentiation

Investigators reported that the human papillomavirus type 8 (HPV8) E6 protein could subvert Hippo signaling by activating Transcriptional Enhanced Associate Domain transcriptional programs that inhibited the expression of keratinocyte differentiation markers.