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e.g. organoids

FBXO21 Mediated Degradation of p85α Regulates Proliferation and Survival of Acute Myeloid Leukemia

Scientists revealed that the ubiquitin E3 ligase, FBXO21, played a critical role in regulating AML pathogenesis, specifically through alterations in PI3K via regulation of p85α protein stability.
[Leukemia]
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