Sex Hormone-Binding Globulin (SHBG) Mitigates ER Stress and Improves Viability and Insulin Sensitivity in Adipose-Derived Mesenchymal Stem Cells (ASC) of Equine Metabolic Syndrome (EMS)-Affected Horses
EMS affected ASC wells were treated with two different concentrations, 50 and 100 nM, of exogenous SHBG, whose biocompatibility was tested after 24, 48, and 72 h of incubation.
[Cell & Bioscience] Scientists demonstrated that CDK1 was correlated with prognosis and was highly expressed in pancreatic cancer tissue and gemcitabine-resistant cells
[Acta Biomaterialia] Researchers demonstrated that incorporating human pancreatic decellularized extracellular matrix within alginate microcapsules resulted in a significant increase in Glucose Stimulation Index and total insulin secreted by encapsulated human islets, compared to free islets and islets encapsulated in only alginate.
[Cancer Letters] In vivo and in vitro experiments revealed that FABP4 induced macrophage-related inflammation to promote pancreatic cancer cell migration, invasion, and metastasis under obese condition.