Inhibitory Role of Bone Marrow Mesenchymal Stem Cells-Derived Exosome in Non-Small-Cell Lung Cancer: microRNA-30b-5p, EZH2, and PI3K/AKT Pathway
Bioinformatics analysis was performed with non-small-cell lung cancer-related miRNA microarray GSE169587 and mRNA data GSE74706 obtained for collection of the differentially expressed miRNAs and mRNAs.
[Cell & Bioscience] Scientists demonstrated that CDK1 was correlated with prognosis and was highly expressed in pancreatic cancer tissue and gemcitabine-resistant cells
[Acta Biomaterialia] Researchers demonstrated that incorporating human pancreatic decellularized extracellular matrix within alginate microcapsules resulted in a significant increase in Glucose Stimulation Index and total insulin secreted by encapsulated human islets, compared to free islets and islets encapsulated in only alginate.
[Cancer Letters] In vivo and in vitro experiments revealed that FABP4 induced macrophage-related inflammation to promote pancreatic cancer cell migration, invasion, and metastasis under obese condition.