Ribonucleotide Reductase Regulatory Subunit M2 (RRM2) as a Potential Sero-Diagnostic Biomarker in Non-small Cell Lung Cancer
Scientists aimed to identify potential novel potential biomarkers for NSCLC. The relative expression of RRM2 mRNA in 30 paired of NSCLC paired tissues was measured by reverse transcription quantitative PCR.
[Cell Metabolism] Using exercise and sarcopenia models, mice lacking IL6Rα on T cells demonstrated deficits in regulatory T cells, their functional maturation, and a more pronounced decline in muscle mass.
[Communications Biology] Based on the up-regulation of catabolism and down-regulation of anabolism, researchers showed genetic mutation-mediated metabolic reprogramming in the progression of cancer cachexia by screening for metabolites and investigating their direct effect on muscle atrophy.
[Acta Pharmacologica Sinica] Researchers investigated the effect of myeloid-derived growth factor to postinjury neointimal formation and the underlying mechanisms. Rat carotid arteries balloon-injured model was established.