Nuclear Translocation of PKM2 Mediates Keratinocyte Metabolic Reprogramming in Psoriasis
Researchers investigated the function of PKM2 in psoriatic keratinocytes. They found that PKM2 expression and its nuclear translocation were induced in the epidermis of psoriasis patients,
[Cell & Bioscience] Scientists demonstrated that CDK1 was correlated with prognosis and was highly expressed in pancreatic cancer tissue and gemcitabine-resistant cells
[Acta Biomaterialia] Researchers demonstrated that incorporating human pancreatic decellularized extracellular matrix within alginate microcapsules resulted in a significant increase in Glucose Stimulation Index and total insulin secreted by encapsulated human islets, compared to free islets and islets encapsulated in only alginate.
[Cancer Letters] In vivo and in vitro experiments revealed that FABP4 induced macrophage-related inflammation to promote pancreatic cancer cell migration, invasion, and metastasis under obese condition.