Development and Functional Evaluation of MDR1-Expressing Microvascular Endothelial-Like Cells Derived from Human iPS Cells as an In Vitro Blood-Brain Barrier Model

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To establish an in vitro model of the human blood-brain barrier, MDR1-overexpressing human induced pluripotent stem cells were generated, and were differentiated to MDR1-expressing brain microvascular endothelial-like cells.
[Journal Of Pharmaceutical Sciences]
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