KLF4 Regulates Skeletal Muscle Development and Regeneration by Directly Targeting P57 and Myomixer

Investigators revealed that Krüppel-like factor 4 (KLF4) played a critical role in skeletal muscle development and regeneration. Specific knockout of KLF4 in skeletal muscle impaired muscle formation further affecting physical activity and also defected skeletal muscle regeneration.
[Cell Death & Disease]
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