Targeting Hyperactive Platelet-Derived Growth Factor Receptor-β Signaling in T Cell Acute Lymphoblastic Leukemia and Lymphoma

The authors reported a novel MYH9::PDGFRB fusion in aT cell lymphoblastic lymphoma patient and demonstrated that this fusion product was constitutively active and sufficient to drive oncogenic transformation in vitro and in vivo.

Stay up-to-date with your field!

Subscribe for free weekly science newsletters.

Related News