Skeletal Muscle-Derived Extracellular Vesicles Transport Glycolytic Enzymes to Mediate Muscle-to-Bone Crosstalk

Researchers identified that skeletal muscle secreted multiple extracellular vesicles (Mu-EVs). These Mu-EVs traveled through the bloodstream to reach bone, where they were phagocytized by bone marrow mesenchymal stem/stromal cells.